TABLE 1.

Results of Visual and Quantitative PET Analyses

Parameter^*	Patients without CSF leak (n = 21)^†	Patients with CSF leak (n = 18)^†	P^‡	ROC AUC^§
Bladder activity at 1 h	1.21 ± 0.68	1.42 ± 0.55	NS
Basal cisterna at:
1 h	1.31 ± 0.64	1.53 ± 0.62	NS
3 h	1.83 ± 0.37	1.74 ± 0.56	NS
5 h	1.81 ± 0.37	1.71 ± 0.56	NS
Cerebral convexities at:
1 h	0.02 ± 0.11	0.03 ± 0.12	NS
3 h	0.71 ± 0.49	0.50 ± 0.59	NS
5 h	1.43 ± 0.83	0.50 ± 0.56	0.0016	0.79
Craniocervical (SO–C1)	0.00 ± 0.00	0.19 ± 0.47	(0.055)	(0.58)
Cervicothoracic (C6–T2)	0.06 ± 0.20	0.68 ± 0.58	0.0001	0.81
Lower thoracic (T7–T12)	0.32 ± 0.63	0.44 ± 0.64	NS
Lumbosacral (L2–S2)	0.75 ± 0.74	0.79 ± 0.81	NS
Consensus summary reading	0.43 ± 0.68	1.39 ± 0.78	0.0006	0.80
PET quantification
t_1/2,biol (h)	9.47 ± 7.03	4.54 ± 2.45	0.0043	0.70
R5/3	0.79 ± 0.16	0.63 ± 0.18	0.0023	0.78

↵* Anatomic localizations refer to sites of tracer accumulation (spinal segments). SO = suboccipital.
↵^† Except for PET quantification (continuous data), all data represent 3-step ordinal scales given as mean values ± SDs across interpreters and times (if not separated) or consensus of raters.
↵^‡ For statistical comparisons of patients without and patients with spinal CSF leak. P values in parentheses indicate trend effects. NS = not significant.
↵^§ Reported only for significant and trend (in parentheses) effects.