TABLE 3.

Distribution of Hypometabolism Patterns and Their Voxel-by-Voxel Concordance with Hypoperfusion Maps in Clinical Groups

¹⁸F-FDG hypometabolism pattern	Dementia			MCI			CU			Whole group
¹⁸F-FDG hypometabolism pattern	Sample (n = 21)	Dice^*	% visual match	Sample (n = 73)	Dice^*	% visual match	Sample (n = 30)	Dice^*	% visual match	Sample (n = 124)	Dice	% visual match
AD-like	10 (all Aβ+)	0.632 ± 0.159	90	25 (all Aβ+)	0.459 ± 0.178	68	4 (all Aβ+)	0.611 ± 0.135	100	39 (all Aβ+)	0.516 ± 0.185	77
FTD-like	5 (3 Aβ+, 2 Aβ−)	0.483 ± 0.201	80	5 (3 Aβ+, 2 Aβ−)	0.531 ± 0.128	100	0			10 (6 Aβ+, 4 Aβ−)	0.507 ± 0.161	90
DLB-like	0			3 (2 Aβ+, 1 Aβ−)	0.467 ± 0.236	100	0			3 (2 Aβ+, 1 Aβ−)	0.467 ± 0.236	100
Limbic-like	0			13 (9 Aβ+, 4 Aβ−)	0.504 ± 0.078	100	1 (all Aβ+)	0.521	100	14 (10 Aβ+, 4 Aβ−)	0.504 ± 0.075	100
Unclassified	6 (5 Aβ+, 1 Aβ−)	0.621 ± 0.071	83	13 (8 Aβ+, 5 Aβ−)	0.498 ± 0.205	100	7 (all Aβ+)	0.381 ± 0.293	86	26 (20 Aβ+, 6 Aβ−)	0.499 ± 0.217	92
Normal	0			14 (6 Aβ+, 8 Aβ−)		86^†	18 (all Aβ+)		94^†	32 (24 Aβ+, 8 Aβ−)		90^†

↵* Average ± SD.
↵^† Percentage of patients consistently negative on ¹⁸F-FDG and early-phase scans.
FTD = frontotemporal dementia; DLB = dementia with Lewy bodies; MCI = mild cognitive impairment; CU = cognitively unimpaired; AD = Alzheimer disease.