TABLE 1.

Patient Demographics and Characteristics for Patients Receiving 68Ga-PSMA-11 per Group Based on Lesion Volume

CharacteristicGroup 1Group 2Group 3P
n9118091
Age (y)67 ± 669 ± 768 ± 80.044
Body mass index (kg/m2)26.6 ± 3.5026.0 ± 3.3026.8 ± 3.810.151
eGFR (mL/min/1.73 m2)76.6 ± 13.176.5 ± 16.176.5 ± 20.80.999
Injection-to-acquisition interval (min)58 ± 1159 ± 1160 ± 90.379
Administered peptide amount (μg)2.83 ± 0.882.58 ± 0.762.52 ± 0.660.015
Injected radioactivity (MBq)111.0 ± 24.9101.1 ± 17.998.6 ± 11.0<0.001
Furosemide during scan51 (56%)138 (77%)70 (77%)0.001
Scanner type<0.001
 Gemini TF Big Bore37 (41%)92 (51%)55 (60%)
 Gemini TF21 (23%)56 (31%)25 (28%)
 Vereos PET/CT33 (36%)32 (18%)11 (12%)
Risk of recurrence<0.001
 Intermediate35 (39%)22 (12%)3 (3%)
 High56 (61%)158 (87%)88 (97%)
Disease spread<0.001
 Local64 (70%)71 (39%)9 (10%)
 Locally advanced26 (29%)82 (46%)45 (50%)
 Oligometastatic1 (1%)24 (13%)28 (31%)
 Metastatic0 (0%)3 (2%)9 (10%)
  • eGFR = estimated glomerular filtration rate.

  • Group 1 is ≤4.11 cm3 (≤Q1), group 2 is 4.11–20.6 cm3, and group 3 is ≥20.6 cm3 (≥Q3). Continuous variables are shown as mean ± SD; categoric variables are shown as number and percentage.