Net Reclassification of Patients with CAD-DL (Explainable Deep Learning Model) Compared With the Same Readers Without CAD-DL
| Reclassified 5-point scale likelihood with CAD-DL | Reclassified likelihood (%) | |||||||
|---|---|---|---|---|---|---|---|---|
| 5-point scale likelihood without CAD-DL | Normal | Probably normal | Equivocal | Probably abnormal | Definitely abnormal | Increased likelihood | Decreased likelihood | Net correctly reclassified |
| Obstructive CAD (n = 360) | 47 (13.1%) | 25 (6.9%) | 6.1% (95% CI 1.4%–10.3%) | |||||
| Normal | 22 | 4 | 2 | 0 | 0 | |||
| Probably normal | 4 | 34 | 10 | 3 | 3 | |||
| Equivocal | 0 | 6 | 10 | 14 | 0 | |||
| Probably abnormal | 0 | 1 | 4 | 24 | 11 | |||
| Definitely abnormal | 0 | 0 | 0 | 10 | 198 | |||
| No Obstructive CAD (n = 360) | 40 (11.1%) | 80 (22.2%) | 11.1% (95% CI 4.8%–16.8%) | |||||
| Normal | 64 | 11 | 0 | 0 | 0 | |||
| Probably normal | 18 | 84 | 11 | 5 | 2 | |||
| Equivocal | 1 | 13 | 11 | 6 | 1 | |||
| Probably abnormal | 0 | 9 | 15 | 29 | 4 | |||
| Definitely abnormal | 1 | 2 | 6 | 15 | 52 | Overall NRI + 17.2% (95% CI 9.2%–24.4%, P < 0.001) | ||
Boldface text indicates studies were reclassified in the correct direction and italicized text indicates studies were reclassified in the incorrect direction. A color version of Table 2 appears in the online supplemental materials.
NRI = net reclassification index.