Diagnostic Performance for PRIMARY Score (1 or 2 vs. 3–5) and PI-RADS (2 vs. 3–5)
| Parameter | PRIMARY score | PI-RADS | ||
|---|---|---|---|---|
| Central read | Reader 1 | Reader 2 | ||
| All patients (n = 291) | ||||
| Sensitivity | 88 (82–93) | 83 (77–89) | ||
| Specificity | 64 (55–73) | 53 (44–62) | ||
| Positive predictive value | 76 (69–82) | 69 (62–75) | ||
| Negative predictive value | 81 (72–88) | 72 (61–80) | ||
| Multiple readers (n = 118) | ||||
| Sensitivity | 88 (77–95) | 83 (71–92) | 92 (82–97) | 82 (70–90) |
| Specificity | 67 (54–79) | 72 (59–83) | 64 (50–76) | 52 (38–65) |
| Positive predictive value | 74 (62–83) | 76 (64–85) | 72 (61–82) | 64 (52–74) |
| Negative predictive value | 85 (71–94) | 81 (67–90) | 88 (74–96) | 73 (57–85) |
| κ PRIMARY score (1 or 2 vs. 3–5) | 0.76 (0.64–0.88) | 0.64 (0.49–0.78) | ||
Data are percentages, with 95% CIs in parentheses.