TABLE 1.

Tissue Classification Based on Radiomic Feature Classes and Signatures in 3-Tissue Model

Classification accuracy	Unharmonized		Harmonized		P
Classification accuracy	Median	Range	Median	Range	P
Gray-level histogram
Training	59.5	57.4–62.1	69.5	66.0–77.1	0.043
Validation	58.9	53.3–61.1	68.3	58.3–73.9	0.043
Gray-level cooccurrence matrix
Training	53.6	47.9–56.7	92.1	88.1–95.2	0.043
Validation	50.0	48.9–55	86.1	80.6–90.6	0.043
Gray-level run-length matrix
Training	62.4	58.8–64.5	84.8	82.4–89.5	0.043
Validation	58.3	57.2–62.8	82.8	73.9–87.8	0.043
Gray-level size-zone matrix
Training	56.2	52.9–57.9	87.6	84.0–89.0	0.042
Validation	52.8	51.7–58.3	85.6	74.4–90.6	0.043
Neighborhood gray-tone difference matrix
Training	54.8	53.3–55.7	79.5	75.5–82.9	0.043
Validation	53.9	50–59.4	77.2	73.9–85.0	0.042
Radiomic signature
Training	62.9	61–63.6	86.9	86.0–90.0	0.043
Validation	58.3	55.6–63.9	84.4	76.7–86.7	0.043