64Cu-DOTA-Trastuzumab Uptake and TTF
| Tumor uptake | Patients > threshold | Patients ≤ threshold | |||||
|---|---|---|---|---|---|---|---|
| Metric | Cut point (g/mL)* | n | Median TTF (mo) | n | Median TTF (mo) | Hazard ratio | P† |
| Day 1 average SUVmax | 4.6 | 5 | 18 | 5 | 3 | 0.3 (0.1−1.3) | 0.10 |
| Day 2 average SUVmax | 5.5 | 6 | 23 | 3 | 2 | 0.1 (0.0−0.9) | 0.01 |
| Day 1 minimum SUVmax | 4.6 | 4 | 26 | 6 | 3 | 0.3 (0.1−1.3) | 0.09 |
| Day 2 minimum SUVmax | 5.5 | 5 | 28 | 4 | 2 | 0.1 (0.0−1.0) | 0.02 |
* Optimal threshold relating uptake to response for individual tumors.
↵†Log rank test.
Hazard ratios are >cut point relative to ≤cut point. Data in parentheses are 95% CIs.