Hematotoxicity and Nephrotoxicity After 177Lu-PSMA-617 PRLT According to Common Terminology Criteria for Adverse Events, version 5.0 (n = 66)
| Numbers of patients with… | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anemia | Leukocytopenia | Thrombocytopenia | Nephrotoxicity | |||||||||
| Grade | Pretherapy | After 2 cycles | Long- term FU | Pretherapy | After 2 cycles | Long- term FU | Pretherapy | After 2 cycles | Long- term FU | Pretherapy | After 2 cycles | Long- term FU |
| CTC-1 | 44 | 45 | 46 | 8 | 12 | 12 | 7 | 12 | 15 | 11 | 12 | 12 |
| CTC-2 | 7 | 14 | 14 | 1 | 3 | 5 | 1 | 2 | 4 | 2 | 1 | 2 |
| CTC-3 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 4 | 0 | 0 | 0 |
| CTC-4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| CTC-5 | NA | 0 | 0 | NA | 0 | 0 | NA | 0 | 0 | NA | 0 | 0 |
FU = follow-up; CTC = Common Terminology Criteria grade; NA = not applicable before therapy (grade 5 represents death).