Diagnostic Values for CU, MIBI Scintigraphy, CU + MIBI Scintigraphy, and 18F-Fluorocholine PET/CT (n = 288)
| Imaging method | TP | FP | TN | FN | Accuracy | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|---|---|---|
| 18F-fluorocholine PET/CT | 148 | 4 | 130 | 1 | 98% (96%–99%) | 99.3% (97%–100%) | 97.0% (95%–99%) | 97.4% (94%–99%) | 99.2% (96%–100%) |
| CU | 112 | 8 | 126 | 37 | 84% (78%–89%) | 75.2% (68%–82%) | 94.0% (90%–98%) | 93.3% (89%–98%) | 77.3% (71%–84%) |
| P | <0.0001 | <0.0001 | 0.25 | ||||||
| MIBI scintigraphy | 97 | 3 | 131 | 52 | 81% (75%–85%) | 65.1% (57%–72%) | 97.8% (95%–100%) | 97.0% (94%–100%) | 71.6% (65%–78%) |
| P | <0.0001 | <0.0001 | 0.47 | ||||||
| CU + MIBI scintigraphy | 134 | 10 | 124 | 15 | 91% (86%–95%) | 89.9% (85%–94%) | 92.5% (88%–97%) | 93.1% (89%–97%) | 89.2% (84%–94%) |
| P | <0.0001 | 0.0009 | 0.09 |
TP = true-positive; FP = false-positive; TN = true-negative; FN = false-negative; PPV = positive predictive value; NPV = negative predictive value.
Data in parentheses are 95% CIs.