Factors Considered for Management of Elevated Tg and Negative DxWBS (Tg+/Scan–) Patients
• Treatment objectives (i.e., cure, progression-free survival, palliation)
• Time interval since last 131I treatment
• Amount of 131I activity administered for most recent treatment
• Response to most recent 131I treatment (if there has been a previous therapy)
• Total cumulative 131I therapeutic activity
• Frequency and severity of side effects of prior 131I therapies
• Is the patient a minimalist or maximalist regarding benefit vs risk of 131I therapy?
• Comorbidities
• Capabilities of the treating facility