Most Relevant mAChR PET Tracers
| Tracer name | Formula | Selectivity |
|---|---|---|
| 18F-FP-TZTP | 3-(4-(3-18F-fluoropropylthio)-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,6-tetrahydropyridine | M2 (M1)* |
| 11C-LSN3172176 | Ethyl-4-(6-(methyl-11C)-2-oxoindolin-1-yl)-[1,4′-bipiperidine]-1′-carboxylate | M1 |
| 11C-MK-6884 | 6-(2-methyl-3-oxoisoindolin-5-yl)-5-(1-((1-methylcyclopentyl)methyl)-1H-pyrazol-4-yl)picolinonitrile | M4 |
* Lower affinity as well reported for M1 (91).
Methodologic determination of selectivity was previously published (91).