TABLE 1.

Overview of Dose Escalation of 68Ga-Exendin4 and Coinjected DO3A-VS-Exendin4 in NHPs

NHP
ScanUnit of measurement12345
kg (body weight)5.65.57.49.06.0
1µg/kg20.050.150.050.0025
MBq11.12.04.62.30.2
2µg/kg12010.5
MBq6.511.16.76.9
3µg/kg10315
MBq5.24.918.7
  • NHPs 2 and 5 were same individual scanned twice, 6 mo apart.