TABLE 3.

90Y-Pentixather Time-Integrated Activity Coefficients in Whole Body, Organs, Tumorous Lesions, Red Marrow, and Blood, as Well as Tissue-Absorbed Doses per Administered Activity in Organs and Lesions (Recalculated from Kinetics Measured with 177Lu-Pentixather)

WBKidneysLiverSpleenRed marrowLesionBlood
Patient no.ã (h)ã (h)D/A (Gy/GBq)ã (h)D/A (Gy/GBq)ã (h)D/A (Gy/GBq)ã (h)D/A (Gy/GBq)D/A (Gy/GBq)ã (h/L)
131.53.033.911.91.181.051.662.30.346.10.19
233.61.903.165.81.910.953.304.00.7718.20.48
335.12.957.326.02.120.531.707.41.420.42
451.62.975.366.31.800.821.586.00.880.28
550.81.223.106.12.651.263.048.41.234.1
640.11.312.125.21.610.401.207.41.099.2
754.23.8712.26.62.970.693.226.51.25
834.53.744.855.41.220.451.075.10.98
958.53.224.296.11.770.671.517.21.06
1032.83.323.754.61.291.070.974.90.720.28
1135.72.834.213.81.160.761.424.70.690.30
1247.21.413.165.41.612.062.5110.11.943.4
1359.34.893.218.51.511.421.058.91.724.7
1449.61.042.157.62.326.633.859.61.85
1567.70.711.486.01.577.406.6923.24.45
1663.82.384.507.81.593.042.707.11.364.20.26
1741.11.392.158.72.311.411.883.10.595.40.44
1834.52.472.675.71.141.581.131.80.273.60.28
1929.93.537.523.61.800.251.533.50.681.50.40
P0.080.53<0.010.550.13<0.01<0.01<0.01<0.01<0.010.31
Minimum29.90.711.482.01.140.250.971.830.271.50.19
First quartile34.51.402.885.31.400.681.314.350.713.70.28
Median41.12.833.756.01.611.051.666.501.064.50.29
Third quartile52.93.274.676.42.021.502.877.881.395.90.41
Maximum67.74.8912.28.72.977.406.6923.24.4518.20.48
Mean44.82.544.275.91.771.712.216.901.226.00.33
SD12.01.142.521.70.511.991.394.610.914.70.10
  • WB = whole body; ã = time-integrated activity coefficient; D/A = tissue-absorbed doses per administered activity.

  • P values are from Shapiro–Wilk test of normality.