Characteristic | Data |
---|---|
Age (y) | 69 (64–74) |
Eastern Cooperative Oncology Group status | |
0 or 1 | 49 (88) |
2 | 7 (12) |
PSA at C1 (μg/L) | 115 (46–476) |
Hemoglobin (reference range [RR], 130–180 g/L) | 122 (110–131) |
Alkaline phosphatase (RR, 30–100 U/L) | 113 (86–231) |
Albumin (RR, 36–52 g/L) | 38 (34–41) |
De novo metastatic disease | 29 (52) |
Gleason score | |
≤7 | 9 (16) |
8–10 | 35 (63) |
Unknown/not available | 12 (21) |
Prior systemic treatments | |
Luteinizing hormone–releasing hormone agonist or antagonist | 56 (100) |
Chemotherapy | 56 (100) |
Docetaxel | 56 (100) |
Cabazitaxel | 53 (91) |
Other chemotherapy | 5 (9) |
ASI | 56 (100) |
Enzalutamide only | 27 (48) |
Abiraterone only | 13 (23) |
Abiraterone + enzalutamide | 16 (29) |
Clinical trial medication | 4 (7) |
PSMA PET | |
SUVmean | 8 (7–10) |
SUVmax | 39 (29–61) |
Volume (L) | 0.64 (0.19–1.21) |
18F-FDG PET | |
SUVmean | 4 (3–5) |
SUVmax | 8 (5–10) |
Volume (L) | 0.07 (0.02–0.31) |
Disease volume | |
<20 metastases | 19 (33) |
≥ 0 metastases | 37 (66) |
Sites of disease on PSMA PET | |
Bone | 49 (88) |
Lymph node | 31 (55) |
Viscera | 12 (21) |
Qualitative data are absolute counts and percentage; continuous data are median and interquartile range.