TABLE 3

Outcome After Treatment

Patient no.Initial diagnosisFirst PTRT cycleFAP PTRT cycles (n)Response* at 6–8 wk after first cycleResponse* at 6–8 wk after third cycle, if applicableTime to progression since initial PTRT (wk)DeathCause of deathSurvival since initial FAP PTRT (mo)
109/201910/20192PD803/2020PD5
203/201910/20192PD806/2020PD8
309/201910/20192PD812/2019Suicide2
402/201810/20192PD802/2020PD4
501/201912/20192PD804/2020PD4
607/201510/20192PD8Patient alive (05/2021)
709/200410/20192PD804/2020PD6
807/201310/20193SDPD24Patient alive (05/2021)
905/200810/20192SD20Patient alive (05/2021)
1003/201510/20192PD801/2020PD3
1102/200910/20191PD601/2020Bronchopneumonia3
  • *Response was evaluated by RECIST 1.1, on 68Ga-FAP-2286 PET/CT (except in patient 5) and tumor marker evaluation after first (in all) and third (in patient 8) PTRT cycles.

  • Response was evaluated on RECIST 1.1 and tumor marker evaluation.

  • FAP = fibroblast activation protein; PTRT = peptide-targeted radionuclide therapy; PD = progressive disease.