68Ga-FAPI PET Accuracy: PPV and Sensitivity of 68Ga-FAPI PET Confirmed by Histopathologic Validation on Per-Patient and Per-Region Basis
| Validation group | Total regions or patients (n) | No. confirmed | No. ruled out | PPV or sensitivity |
|---|---|---|---|---|
| PPV | ||||
| Histopathologic validation | ||||
| PET-positive (per patient) | 27 | 27 (100%) | 0 (0%) | 1.00 (95% CI, 0.87 to 1.00) |
| PET-positive (per region) | 33 | 32 (97%) | 1 (3%) | 0.97 (95% CI, 0.84 to 1.00) |
| Sensitivity | ||||
| Histopathologic findings | ||||
| Confirmed (per patient) | 28 | 27 (96%)* | 1 (4%)† | 0.96 (95% CI, 0.82 to 1.00) |
| Confirmed (per region) | 34 | 32 (94%)* | 2 (6%)† | 0.94 (95% CI, 0.80 to 0.99) |
*PET-positive.
↵†PET-negative.