TABLE 1

Coefficients of Determination and Regression Coefficients for Prediction of Aβ PET Signal by Fibrillar and Nonfibrillar Aβ Components, with Additional Factoring for Heterogeneity (in Mice with Equal Genotype at Single Time Point) and Age

Model	R²	Corrected R²	B Fibrillar	B Nonfibrillar	P
Fibrillar	0.499	0.497	4.414 (3.915–4.926)		<0.001
Nonfibrillar	0.324	0.322		0.477 (0.378–0.569)	<0.001
Fibrillar × nonfibrillar	0.574	0.571	3.521 (2.954–4.041)	0.259 (0.178–0.341)	<0.001
Fibrillar × nonfibrillar × heterogeneity	0.854	0.852	3.521 (2.954–4.041)	0.259 (0.178–0.341)	<0.001
Fibrillar × nonfibrillar × heterogeneity × age	0.928	0.927	2.810 (2.620–3.032)	0.146 (0.103–0.193)	<0.001

R² = coefficient of determination; B = regression coefficient.
Numbers in parentheses represent 95% CIs as assessed by bootstrapping with 1,000 random samples.