List of Common and Emerging Radiopharmaceutical Therapeutics, Their Clinical Indications, and Typical Dose-Limiting Tissues
| Radiopharmaceutical | Indication | Dose-limiting tissues |
|---|---|---|
| 131I-NaI | Thyroid cancers | Marrow, lungs (20,21) |
| 90Y-microspheres | Intrahepatic tumors, including primary and metastatic disease | Liver, lungs, stomach (22) |
| 177Lu-DOTATATE | Low-grade neuroendocrine tumors | Marrow, kidneys (23) |
| 131I-MIBG | Paraganglioma, pheochromocytoma | Marrow, kidneys, liver (24,25) |
| 223RaCl2 | Metastatic castration-resistant prostate cancer (mCRPC) | Marrow, gastrointestinal (26) |
| 177Lu-PSMA-617 (investigational) | Metastatic castration-resistant prostate cancer (mCRPC) | Marrow, salivary glands, kidneys (27) |
| 177Lu-DOTATOC (investigational) | Low-grade neuroendocrine tumors | Marrow, kidneys (28) |
| 131I-Iomab-B (investigational) | Acute myeloid leukemia (AML) | Liver (29) |