TABLE 3

iPET Reference Parameters, Lesion-Based Parameters, DTTV Parameters, and First-Order Heterogeneity Measures, Part 1

iPETAll patients (n = 36)Responders (n = 30)Nonresponders (n = 6)P*
Reference tissue
 SUVmax liver0.011
  Mean (SD)5.8 (1.8)6.1 (1.8)4.2 (1.2)
  Minimum–maximum2.8–11.23.6–11.22.8–6.4
 SUVmax spleen0.0085
  Mean (SD)19.4 (10.6)21.2 (10.7)10.6 (3.8)
  Minimum–maximum4.3–49.17.3–49.14.3–14.6
Lesion based
 Mean SUVmax0.048
  Mean (SD)34.3 (19.4)37 (20.2)21.2 (6)
  Minimum–maximum6.8–93.16.8–93.112.4–29.9
 Mean SUVmax T/L0.57
  Mean (SD)6.1 (3.2)6.3 (3.5)5.2 (1.4)
  Minimum–maximum0.9–17.40.9–17.42.9–6.8
 Mean SUVmax T/S0.92
  Mean (SD)2.1 (1.2)2.1 (1.3)2.2 (0.9)
  Minimum–maximum0.1–6.10.1–6.11.5–3.9
  • * P value.

  • Measured in cubic centimeters.

  • DTTV SUVmean liver = SUVmean in segmented volume obtained with liver as threshold; DTTV SUVmean spleen = SUVmean in segmented volume obtained with spleen as threshold; DTTV liver = DTTV obtained with liver as threshold; DTTV spleen = DTTV obtained with spleen as threshold; DTTV SUVmean liver = DTTV SUVmean obtained with liver as threshold; DTTV SUVmean spleen = DTTV SUVmean obtained with spleen as threshold; CoV = coefficient of variation.

  • Wilcoxon rank sum test P values are shown.