Posttreatment Renal and Bone Marrow Toxicity Assessment
| Cycle 1 | Cycle 2 | |||||
|---|---|---|---|---|---|---|
| Parameter | Baseline | 1 mo | 2 mo | 1 mo | 2 mo | 6 mo |
| Creatinine (mg/dL) | ||||||
| Subject 1 | 1.20 | 1.1 | 1.10 | 1.30 | 1.10 | 1.60 |
| Subject 2 | 1.10 | 0.86 | 0.94 | 0.98 | 1.13 | 1.00 |
| Subject 3 | 1.10 | 1.14 | 0.95 | 1.00 | 1.07 | 1.10 |
| Platelet (k/mm3) | ||||||
| Subject 1 | 396 | 151 | 215 | 191 | 216 | 165 |
| Subject 2 | 187 | 82 | 128 | 86 | 130 | 189 |
| Subject 3 | 253 | 107 | 150 | 111 | 47 | 173 |
| Absolute neutrophil count (cells/mm3) | ||||||
| Subject 1 | 5,050 | 6,510 | 4,310 | 5,630 | 4,560 | 4,100 |
| Subject 2 | 6,510 | 4,500 | 3,800 | 4,100 | 4,800 | 5,180 |
| Subject 3 | 3,230 | 3,393 | 1,575 | 3,281 | 1,332 | 3,520 |