TABLE 3

Comparison of 68Ga-PSMA11 Uptake in Normal Organs in Control and MSG Scans

SUVmeanSUVmax
SiteControlMSGChangePControlMSGChangeP
Oral ingestion (n = 8)
 Lacrimal glands5.5 ± 2.32.6 ± 0.9−50.9% ± 6.5%0.0019.9 ± 4.74.3 ± 1.6−55.5% ± 6.1%0.002
 Parotid glands10.9 ± 4.16.9 ± 3.3−32.9% ± 22.6%0.00219.0 ± 6.613.2 ± 6.2−34.1% ± 21.7%0.020
 Submandibular glands15.9 ± 5.76.6 ± 2.5−58.9% ± 8.9%<0.00129.0 ± 10.510.4 ± 3.7−63.2% ± 9.9%<0.001
 Salivary glands12.1 ± 4.66.8 ± 3.1−45.5% ± 14.6%0.00429.0 ± 10.513.5 ± 5.9−53.4% ± 11.1%<0.001
 Liver4.6 ± 0.52.1 ± 0.3−54.2% ± 5.3%<0.00110.7 ± 1.35.5 ± 0.4−50.1% ± 8.3%<0.001
 Spleen8.1 ± 2.03.0 ± 0.9−62.8% ± 6.9%<0.00113.7 ± 3.55.3 ± 1.5−61.5% ± 8.6%<0.001
 Kidney34.5 ± 14.817.4 ± 8.8−51.5% ± 13.7%<0.00163.6 ± 25.032.7 ± 16.6−51.3% ± 13.3%<0.001
 Urinary bladder16.0 ± 8.769.1 ± 34.3+371.6% ± 300.2%0.00433.7 ± 23.9184.2 ± 97.5+593.2% ± 659.5%0.003
 Total tumor lesions6.6 ± 3.53.5 ± 2.1−45.0% ± 19.0%0.02321.5 ± 19.88.2 ± 8.7−55.7% ± 22.0%0.061
Swishing (n = 8)
 Lacrimal glands6.5 ± 1.66.0 ± 2.5+4.9% ± 22.0%0.62512.3 ± 3.211.1 ± 4.6−5.2% ± 25.0%0.556
 Parotid glands11.7 ± 2.212.0 ± 2.7+0.1% ± 8.4%0.91722.2 ± 6.122.5 ± 6.0+1.9% ± 10.4%0.792
 Submandibular glands12.8 ± 3.513.4 ± 3.6+5.6% ± 6.8%0.06121.3 ± 7.022.6 ± 7.3+7.7% ± 11.6%0.188
 Salivary glands11.5 ± 2.311.9 ± 2.9+1.6% ± 7.8%0.52125.8 ± 6.026.6 ± 7.2+4.3% ± 12.3%0.442
 Liver4.1 ± 0.84.3 ± 0.9+5.7% ± 17.3%0.3179.8 ± 1.310.4 ± 3.0+5.3% ± 15.7%0.321
 Spleen6.1 ± 2.06.3 ± 1.7+6.2% ± 18.6%0.45810.8 ± 3.910.1 ± 2.6−0.3% ± 15.2%0.622
 Kidney30.1 ± 8.030.1 ± 5.8+ 1.9% ± 13.9%0.95857.1 ± 15.957.6 ± 13.6+3.4% ± 15.8%0.782
 Urinary bladder20.2 ± 13.524.2 ± 8.3+36.5% ± 41.4%0.35750.6 ± 42.456.4 ± 20.2+52.0% ± 70.0%0.651
Total tumor lesions4.9 ± 1.15.4 ± 1.67.8% ± 13.8%0.12512.5 ± 7.715.0 ± 11.312.6% ± 27.8%0.196
  • Data are average ± SD.