Multivariate Survival Analysis of Changes of 18F-FET PET Imaging Parameters
| Parameter | Multivariate PFS analysis | Multivariate OS analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| TBRmax change | 2.920 | 1.272–6.705 | 0.012* | 2.660 | 1.144–6.189 | 0.023* |
| MTV change | 1.925 | 0.842–4.404 | 0.121† | 3.614 | 1.481–8.820 | 0.005† |
↵* Compared with age, EOR, MGMT promoter methylation status, and TBRmax baseline.
↵† Compared with age, EOR, MGMT promoter methylation status, and MTV baseline.
MTV = metabolic tumor volume; PFS = progression-free survival; PR = partial response/partial resection; TBRmax = maximum tumor-to-brain ratio.