Patient | Cohort | Cancer type | EGFR H score | Best response on M11-849 study | Best response on M12-326 study |
1 | 1 | Colon | 0 | Clinically stable | PD |
2 | 1 | NSCLC | 3 | Clinically stable | PD |
3 | 1 | HGG | 50 | Clinically stable | PD |
4 | 1 | H&N | 12 | Clinically stable | PD |
5 | 1 | HGG | 295 | Clinically stable | PD |
6 | 1 | Adrenal | 0 | Clinically stable | SD |
7 | 2 | H&N | 80 | PD | N/A* |
8 | 2 | H&N | 235 | SD | PR |
9 | 2 | Thymoma | 115 | PD | N/A* |
10 | 2 | Cholangio-carcinoma | 55 | PD | N/A* |
11 | 2 | NSCLC | 278 | SD | PD |
12 | 2 | Colon | 0 | SD | PD |
13 | 2 | H&N | 170 | SD | PD |
14 | 2 | Cervical | 13 | PD | N/A* |
15 | 2 | Bladder | 228 | PD | N/A* |
16 | 2 | H&N | 67 | PD | N/A* |
17 | 2 | Colon | 0 | SD | PD |
18 | 2 | H&N | 32 | PD | N/A* |
↵* Patients who had progressive disease at the end of M11-849 study were not eligible for enrolment on the M12-326 extension study.
PD = progressive disease; NSCLC = non–small cell lung cancer; HGG = high-grade glioma; H&N = head and neck; SD = stable disease; N/A = not applicable; PR = partial response.