TABLE 2

Individual Patient Data

PatientCohortCancer typeEGFR H scoreBest response on M11-849 studyBest response on M12-326 study
11Colon0Clinically stablePD
21NSCLC3Clinically stablePD
31HGG50Clinically stablePD
41H&N12Clinically stablePD
51HGG295Clinically stablePD
61Adrenal0Clinically stableSD
72H&N80PDN/A*
82H&N235SDPR
92Thymoma115PDN/A*
102Cholangio-carcinoma55PDN/A*
112NSCLC278SDPD
122Colon0SDPD
132H&N170SDPD
142Cervical13PDN/A*
152Bladder228PDN/A*
162H&N67PDN/A*
172Colon0SDPD
182H&N32PDN/A*
  • * Patients who had progressive disease at the end of M11-849 study were not eligible for enrolment on the M12-326 extension study.

  • PD = progressive disease; NSCLC = non–small cell lung cancer; HGG = high-grade glioma; H&N = head and neck; SD = stable disease; N/A = not applicable; PR = partial response.