| (R)-18F-OF-Me-NB1 n=1 | (R)-11C-NR2B-Me n=2 | (S)-18F-OF-NB1 n=2 | |
| fP | 1.2% | 0.7% | 15% |
| Baseline VT range (mL/cm3) | 8.2-12.8 | 23.5-54.6 | 16.9-38.8 |
| VND (mL/cm3) | 6.4 | 11.2 | 8.3 |
| Mean cortical BPND | 0.65 | 2.64 | 2.53 |
| GluN2B blocking | |||
| Co-101,244 (0.25 mg/kg) | 77% | 95% | 85% |
| σ1 blocking | |||
| FTC-146 (0.027 mg/kg) | 30% | 49% | |
| FTC-146 (0.125 mg/kg) | 56% | 48% |