FDA-Approved Antiresorptive and Anabolic Therapies Used in Randomized Clinical Trials (53,54)

DrugName of studyNo. of patientsRR% of vertebral FxRR% of hip Fx
Antiresorptive therapies
 Zoledronic acidHORIZON7,7657041
Anabolic therapies
 AbaloparatideACTIVE2,4638643 (NV Fx)
  • * identifier.

  • RR = relative risk reduction; Fx = fracture; HRT/ERT = hormone replacement therapy/estrogen replacement therapy; NS = not significant; NA = not available; NV Fx = nonvertebral fracture.