RT Journal Article SR Electronic T1 Advances in Imaging Reactive Oxygen Species JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 457 OP 461 DO 10.2967/jnumed.120.245415 VO 62 IS 4 A1 Eli M. Espinoza A1 Joachim Justad Røise A1 I-Che Li A1 Riddha Das A1 Niren Murthy YR 2021 UL http://jnm.snmjournals.org/content/62/4/457.abstract AB Reactive oxygen species (ROS) play a pivotal role in many cellular processes and can be either beneficial or harmful. The design of ROS-sensitive fluorophores has allowed for imaging of specific activity and has helped elucidate mechanisms of action for ROS. Understanding the oxidative role of ROS in the many roles it plays allows us to understand the human body. This review provides a concise overview of modern advances in the field of ROS imaging. Indeed, much has been learned about the role of ROS throughout the years; however, it has recently been shown that using nanoparticles, rather than individual small organic fluorophores, for ROS imaging can further our understanding of ROS.