PT  - JOURNAL ARTICLE
AU  - Niren Murthy
AU  - Eli Misael Espinoza
AU  - Joachim Justad Roeise
AU  - I-Che Li
AU  - Riddha Das
TI  - Advances in Reactive Oxygen Species (ROS) Imaging
AID  - 10.2967/jnumed.120.245415
DP  - 2020 Dec 01
TA  - Journal of Nuclear Medicine
PG  - jnumed.120.245415
4099  - http://jnm.snmjournals.org/content/early/2020/12/31/jnumed.120.245415.short
4100  - http://jnm.snmjournals.org/content/early/2020/12/31/jnumed.120.245415.full
AB  - Reactive oxygen species (ROS) play a pivotal role in many cellular processes and can either be beneficial or harmful. Design of ROS sensitive fluorophores has allowed for imaging of specific activity and has helped elucidate mechanisms of action for ROS. Understanding the oxidative role of ROS in the many roles it plays allows us to understand the human body. This review provides a concise overview of modern advances in the field of ROS imaging. Indeed, much has been learned about the role of ROS throughout the years, however it has recently been shown that using nanoparticles, rather than individual small organic fluorophores, for ROS imaging can further our understanding of ROS.