RT Journal Article
SR Electronic
T1 Immune Checkpoint Imaging in Oncology: A Game Changer Toward Personalized Immunotherapy?
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1137
OP 1144
DO 10.2967/jnumed.119.237891
VO 61
IS 8
A1 Susanne Lütje
A1 Georg Feldmann
A1 Markus Essler
A1 Peter Brossart
A1 Ralph A. Bundschuh
YR 2020
UL http://jnm.snmjournals.org/content/61/8/1137.abstract
AB Immune checkpoint blockade represents a promising approach in oncology, showing antitumor activities in various cancers. However, although being generally far better tolerated than classic cytotoxic chemotherapy, this treatment, too, may be accompanied by considerable side effects and not all patients benefit equally. Therefore, careful patient selection and monitoring of the treatment response is mandatory. At present, checkpoint-specific molecular imaging is being increasingly investigated as a tool for patient selection and response evaluation. Here, an overview of the current developments in immune checkpoint imaging is provided.