TY - JOUR T1 - Most intended management changes after <sup>68</sup>Ga-DOTATATE PET/CT are implemented JF - Journal of Nuclear Medicine JO - J Nucl Med DO - 10.2967/jnumed.117.192450 SP - jnumed.117.192450 AU - Jérémie Calais AU - Johannes Czernin AU - Matthias Eiber AU - Wolfgang Peter Fendler AU - Jeannine Gartmann AU - Anthony Heaney AU - Andrew Hendifar AU - Joseph Pisegna AU - Joel Randolph Hecht AU - Edward Wolin AU - Roger Slavik AU - Pawan Gupta AU - Andrew Quon AU - Christiaan Schiepers AU - Martin Allen-Auerbach AU - Ken Herrmann Y1 - 2017/05/01 UR - http://jnm.snmjournals.org/content/early/2017/05/03/jnumed.117.192450.abstract N2 - Background: In this prospective referring physician based survey, we investigated the definite clinical impact of 68Ga-DOTATATE positron emission tomography / computed tomography (PET/CT) on managing patients with neuroendocrine tumors (NET). Methods: We prospectively studied 130 patients with 68Ga-DOTATATE PET/CT referred for initial or subsequent management decisions (NCT02174679). Referring physicians completed one questionnaire prior to the scan (Q1) to indicate the treatment plan without PET/CT information; one immediately after review of the imaging report to denote intended management changes (Q2); and one 6 months later (Q3) to verify whether intended changes were in fact implemented. To further validate the Q3 responses a systematic electronic chart review was conducted. Results: All 3 questionnaires were completed by referring physicians for 96/130 patients (74%). 68Ga-DOTATATE PET/CT resulted in intended treatment management changes (Q2) in 48/96 patients (50%). These changes were finally implemented (Q3) in 36/48 patients (75%). Q3 responses have been confirmed in all patients with available electronic chart (36/96; 38%). Conclusion: This prospective study confirms a significant impact of 68Ga-DOTATATE PET/CT on intended management of patients with NET (50% of changes) and notably demonstrates a high implementation rate (75%) of these intended management changes. ER -