RT Journal Article
SR Electronic
T1 Metabolic and Molecular Imaging of Atherosclerosis and Venous Thromboembolism
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP jnumed.116.182873
DO 10.2967/jnumed.116.182873
A1 Osborn, Eric A
A1 Kessinger, Chase W
A1 Tawakol, Ahmed
A1 Jaffer, Farouc A
YR 2017
UL http://jnm.snmjournals.org/content/early/2017/04/19/jnumed.116.182873.abstract
AB Metabolic and molecular imaging continues to advance our understanding of vascular disease pathophysiology. At present, 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) imaging is the most widely utilized clinical tool for metabolic and molecular imaging of atherosclerosis. However, novel nuclear tracers and intravascular optical near-infrared fluorescence (NIRF) imaging catheters are emerging to assess new biological targets in vivo and in coronary arteries. This review highlights current metabolic and molecular imaging clinical and near-clinical applications within atherosclerosis and venous thromboembolism (VTE), and explores the potential for metabolic and molecular imaging to impact patient-level risk prediction and disease treatment.