PT - JOURNAL ARTICLE AU - Osborn, Eric A AU - Kessinger, Chase W AU - Tawakol, Ahmed AU - Jaffer, Farouc A TI - Metabolic and Molecular Imaging of Atherosclerosis and Venous Thromboembolism AID - 10.2967/jnumed.116.182873 DP - 2017 Apr 01 TA - Journal of Nuclear Medicine PG - jnumed.116.182873 4099 - http://jnm.snmjournals.org/content/early/2017/04/19/jnumed.116.182873.short 4100 - http://jnm.snmjournals.org/content/early/2017/04/19/jnumed.116.182873.full AB - Metabolic and molecular imaging continues to advance our understanding of vascular disease pathophysiology. At present, 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) imaging is the most widely utilized clinical tool for metabolic and molecular imaging of atherosclerosis. However, novel nuclear tracers and intravascular optical near-infrared fluorescence (NIRF) imaging catheters are emerging to assess new biological targets in vivo and in coronary arteries. This review highlights current metabolic and molecular imaging clinical and near-clinical applications within atherosclerosis and venous thromboembolism (VTE), and explores the potential for metabolic and molecular imaging to impact patient-level risk prediction and disease treatment.