RT Journal Article
SR Electronic
T1 Quantification of Rotational Thallium-201 Myocardial Tomography
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 17
OP 26
VO 26
IS 1
A1 Ernest V. Garcia
A1 Kenneth Van Train
A1 Jamshid Maddahi
A1 Florence Prigent
A1 John Friedman
A1 Joseph Areeda
A1 Alan Waxman
A1 Daniel S. Berman
YR 1985
UL http://jnm.snmjournals.org/content/26/1/17.abstract
AB A comprehensive method is described for quantification of the relative 3-dimensional distribution of TI-201 in the myocardium, following stress and subsequent washout. The method uses maximal-count circumferential profiles of well-defined long- and short-axis tomograms to determine the 3-dimensional distribution of TI-201; it then maps this distribution onto a 2-dimensional polar representation. Abnormal thallium distribution or washout is identified by automatic computer comparison of each patient's profile with the corresponding lower limits of normal profiles. Abnormality is expressed as a percentage of the entire myocardium by use of polar maps for extent and severity. The binary extent map states whether a given location is normal or abnormal, and the severity map expresses the degree of abnormality. Preliminary criteria for abnormality were derived from the tomographic results of 25 normals and 28 patients with documented coronary artery disease. The results were normal in 23 of the 25 normals and were abnormal in 25 of the 28 CAD patients. In addition, the computer output correctly localized the presence or absence of disease in 46 of 56 coronary circulations.