PT  - JOURNAL ARTICLE
AU  - Irene Lemish
AU  - Francis Bennett
AU  - Clayton Martin
AU  - Anthony Warwick
AU  - Michael Quinlan
TI  - A Sensitive Human Thyroglobulin RIA to Define Clearly the Presence or Absence of Functioning Thyroid Tissue
DP  - 1984 Jan 01
TA  - Journal of Nuclear Medicine
PG  - 49--55
VI  - 25
IP  - 1
4099  - http://jnm.snmjournals.org/content/25/1/49.short
4100  - http://jnm.snmjournals.org/content/25/1/49.full
SO  - J Nucl Med1984 Jan 01; 25
AB  - This paper describes a practical procedure to establish a sensitive radioimmunoassay for the measurement of human thyroglobulin (HTg) in serum. The assay enables a clear distinction to be made between levels of HTg indicating the presence or absence of functioning thyroid tissue. It compares the use of HTg serum levels with the conventional I-131 scintigram as a marker for recurrent thyroid cancer. In addition, a simple and sensitive radioimmunologic assay is described for the determination of serum antithyroglobulin autoantibodies, the presence of which may give falsely elevated HTg levels.