PT - JOURNAL ARTICLE AU - Zheng, Dong AU - Liu, Jiajin AU - li, ke AU - Lin, Mu AU - Xu, Baixuan AU - Tian, Jiahe TI - <strong><sup>18</sup></strong><strong>F-FDG PET/MR Imaging with Non-contrast MRI in Patients with Gastric cancer</strong> DP - 2020 May 01 TA - Journal of Nuclear Medicine PG - 204--204 VI - 61 IP - supplement 1 4099 - http://jnm.snmjournals.org/content/61/supplement_1/204.short 4100 - http://jnm.snmjournals.org/content/61/supplement_1/204.full SO - J Nucl Med2020 May 01; 61 AB - 204Purpose: Evaluate the feasibility of fluorine-18 (18F) fluorodeoxyglucose (FDG) positron emission tomography (PET) and non-contrast magnetic resonance (MR) imaging in patients with gastric cancer by optimizing the scan protocol and to compare the image quality to 18F FDG PET and computed tomography (CT). Methods: The PET/CT and PET/MR imaging were sequentially performed in 30 patients with gastric cancer diagnosed by gastroscope using a single-injection-with-dual-imaging protocol. After intravenous injection of 18F-FDG (mean, 249 MBq), PET/CT imaging including low-dose CT was performed (mean uptake time, 47 ± 6 min), and PET/MR imaging including a T1-weighted Dixon sequence for attenuation correction and two different T2-weighted sequences was subsequently acquired (88 ± 15 min after 18F-FDG injection). Four series of images (CT from PET/CT, T1W, T2W Half-Fourier acquisition single-shot turbo spin-echo [T2W-HASTE] and T2W-BLADE from PET/MR) were visually evaluated using a 3-4 points scale for: (1) image artifacts, (2) lesion conspicuity and (3) image fusion quality. The characteristics of the primary lesions were assessed and compared between the PET/CT and PET/MR acquisitions. Results: The image quality and lesion conspicuity of the T2W-HASTE images were significantly improved compared to that of the T2W-BLADE images. A significantly higher number of artifacts were seen in the T2W-HASTE images compared with the T1W and CT images (p &lt; 0. 05). No differences in the accuracy of image fusion between PET/MR and PET/CT (p &gt; 0. 05); however, significant difference was seen in the lesion conspicuity measurements (p &lt; 0.05) with T2W-HASTE being superior. For information about the primary lesion characteristics, the T2W-HASTE images provided the most successful identifications compared with those of the T1W and PET/CT (13vs7vs5) images. Conclusions: PET/MR with the T2W-HASTE was better at revealing the details of local stomach lesions compared with PET/CT imaging. Combining the PET/MR with the T2W-HASTE technique is a promising imaging method for diagnosing and staging gastric cancer. View this table:Table1 MRI Parameters View this table:Table2 The inter observer agreement between two readers (Kappa value) View this table:Table3 Comparison of image artifacts and lesion conspicuity between two T2W sequences View this table:Table4Comparison of image artifacts, lesion conspicuity and image fusion quality in three modalities