RT Journal Article
SR Electronic
T1 <strong>Clinical value of <sup>99m</sup></strong><strong>Tc-deoxy-glucose </strong>derivative SPECT/CT in tumors
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1293
OP 1293
VO 61
IS supplement 1
A1 Jing Niu
A1 Haiyan Liu
A1 Junbo Zhang
A1 Wanting Li
A1 Jingfen Kang
A1 Caihong Li
A1 Zhiyong Shi
A1 Suyun Yang
A1 Hongliang Wang
A1 Zhifang Wu
A1 Sijin Li
YR 2020
UL http://jnm.snmjournals.org/content/61/supplement_1/1293.abstract
AB 1293Objectives: To explore the clinical application and prospect of 99mTc-deoxy-glucose derivative (99mTc-CN5DG) SPECT /CT in tumor diagnosis. Methods: 99mTc-CN5DG SPECT/CT and 18F-FDG PET/CT imaging were performed respectively in 15 patients (8 males and 7 females, mean age 58.73±13.40 years) in one week before surgery. They were clinically suspected or diagnosed tumors. SPECT/CT fusion images were used to delineate the ROI of the lesion, and the healthy side areas to delineate the ROI of the same range. For PET/CT fusion images, the same method was used to obtain the target/non-target ratio. The images were analyzed by visual analysis and semi-quantitative analysis. SPSS 22.0 software was used for data analysis. Results: Take pathological results as the gold standard. 99mTc-CN5DG SPECT/CT imaging showed 11 uptake of the imaging agent, including 9 lesions of the brain, 1 scapular metastasis, and 1 sacral metastasis. 18F-FDG PET/CT imaging was performed in all 17 lesions. In the semi-quantitative analysis of 17 lesions, there were 13 uptake of 99mTc-CN5DG SPECT/CT imaging, including 9 brain lesions, 1 scapular metastasis, 1 sacral metastasis, 1 endometrial lesion and 1 lung lesion. 18F-FDG PET/CT imaging showed that all 17 lesions were ingested. Conclusions: The diagnostic value of 99mTc-CN5DG SPECT/CT in brain lesions is very consistent with that of 18F-FDG, suggesting that 99mTc-CN5DG SPECT/CT has certain clinical value in the detection of brain lesions. The diagnostic value of tumors in other sites should be further discussed by increasing the sample size. Key words: 99mTc-deoxy-glucose derivative; SPECT/CT; 18F-FDG; PET/CT