RT Journal Article
SR Electronic
T1 Genetic Determinants of Pheochromocytoma and Paraganglioma Imaging Phenotypes
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 643
OP 645
DO 10.2967/jnumed.120.245613
VO 61
IS 5
A1 David Taïeb
A1 Karel Pacak
YR 2020
UL http://jnm.snmjournals.org/content/61/5/643.abstract
AB Parallel to the application of new PET radiopharmaceuticals for pheochromocytoma and paraganglioma (collectively named PPGLs) imaging, several studies have increased our understanding on their biology, genetics, metabolomics, and embryologic origin. In this review, we highlight the current relationship between genotypes and molecular imaging phenotypes. Additionally, we summarize the referral guidelines for imaging of PPGL patients with or without knowledge of their genetic background.