RT Journal Article
SR Electronic
T1 Introduction to Radiomics
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 488
OP 495
DO 10.2967/jnumed.118.222893
VO 61
IS 4
A1 Mayerhoefer, Marius E.
A1 Materka, Andrzej
A1 Langs, Georg
A1 Häggström, Ida
A1 Szczypiński, Piotr
A1 Gibbs, Peter
A1 Cook, Gary
YR 2020
UL http://jnm.snmjournals.org/content/61/4/488.abstract
AB Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative metrics—the so-called radiomic features—within medical images. Radiomic features capture tissue and lesion characteristics such as heterogeneity and shape and may, alone or in combination with demographic, histologic, genomic, or proteomic data, be used for clinical problem solving. The goal of this continuing education article is to provide an introduction to the field, covering the basic radiomics workflow: feature calculation and selection, dimensionality reduction, and data processing. Potential clinical applications in nuclear medicine that include PET radiomics-based prediction of treatment response and survival will be discussed. Current limitations of radiomics, such as sensitivity to acquisition parameter variations, and common pitfalls will also be covered.