RT Journal Article
SR Electronic
T1 Development of Dedicated Brain PET Imaging Devices: Recent Advances and Future Perspectives
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1044
OP 1052
DO 10.2967/jnumed.118.217901
VO 60
IS 8
A1 Ciprian Catana
YR 2019
UL http://jnm.snmjournals.org/content/60/8/1044.abstract
AB Whole-body PET scanners are not optimized for imaging small structures in the human brain. Several PET devices specifically designed for this task have been proposed either for stand-alone operation or as MR-compatible inserts. The main distinctive features of some of the most recent concepts and their performance characteristics, with a focus on spatial resolution and sensitivity, are reviewed. The trade-offs between the various performance characteristics, desired capabilities, and cost that need to be considered when designing a dedicated brain scanner are presented. Finally, the aspirational goals for future-generation scanners, some of the factors that have contributed to the current status, and how recent advances may affect future developments in dedicated brain PET instrumentation are briefly discussed.