PT - JOURNAL ARTICLE AU - Tobias Maurer AU - Markus Graefen AU - Henk van der Poel AU - Freddie Hamdy AU - Alberto Briganti AU - Matthias Eiber AU - Hans-Jürgen Wester AU - Fijs W.B. van Leeuwen TI - Prostate-Specific Membrane Antigen–Guided Surgery AID - 10.2967/jnumed.119.232330 DP - 2020 Jan 01 TA - Journal of Nuclear Medicine PG - 6--12 VI - 61 IP - 1 4099 - http://jnm.snmjournals.org/content/61/1/6.short 4100 - http://jnm.snmjournals.org/content/61/1/6.full SO - J Nucl Med2020 Jan 01; 61 AB - Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)–ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.