PT - JOURNAL ARTICLE AU - Soleen Ghafoor AU - Irene A. Burger AU - Alberto H. Vargas TI - Multimodality Imaging of Prostate Cancer AID - 10.2967/jnumed.119.228320 DP - 2019 Oct 01 TA - Journal of Nuclear Medicine PG - 1350--1358 VI - 60 IP - 10 4099 - http://jnm.snmjournals.org/content/60/10/1350.short 4100 - http://jnm.snmjournals.org/content/60/10/1350.full SO - J Nucl Med2019 Oct 01; 60 AB - Prostate cancer is a very heterogeneous disease, and contemporary management is focused on identification and treatment of the prognostically adverse high-risk tumors while minimizing overtreatment of indolent, low-risk tumors. In recent years, imaging has gained increasing importance in the detection, staging, posttreatment assessment, and detection of recurrence of prostate cancer. Several imaging modalities including conventional and functional methods are used in different clinical scenarios with their very own advantages and limitations. This continuing medical education article provides an overview of available imaging modalities currently in use for prostate cancer followed by a more specific section on the value of these different imaging modalities in distinct clinical scenarios, ranging from initial diagnosis to advanced, metastatic castration-resistant prostate cancer. In addition to established imaging indications, we will highlight some potential future applications of contemporary imaging modalities in prostate cancer.