PT - JOURNAL ARTICLE AU - Ivis F. Chaple AU - Suzanne E. Lapi TI - Production and Use of the First-Row Transition Metal PET Radionuclides <sup>43,44</sup>Sc, <sup>52</sup>Mn, and <sup>45</sup>Ti AID - 10.2967/jnumed.118.213264 DP - 2018 Nov 01 TA - Journal of Nuclear Medicine PG - 1655--1659 VI - 59 IP - 11 4099 - http://jnm.snmjournals.org/content/59/11/1655.short 4100 - http://jnm.snmjournals.org/content/59/11/1655.full SO - J Nucl Med2018 Nov 01; 59 AB - With the increasing focus on a more personalized approach to medicine using imaging techniques to select patients for targeted treatment or theranostic strategies, interest in the development of new radionuclides is expanding. Through the development of production and radiochemistry techniques, several new radiometals are being added to the toolbox of the nuclear imaging community. 43,44g,mSc, 52gMn, and 45Ti are all emerging transition metal radionuclides and will be discussed in this short review. Each of these nuclides has unique imaging characteristics and shows promise for the development of new molecular imaging agents.