%0 Journal Article %A Carlos F. Uribe %A Sulantha Mathotaarachchi %A Vincent Gaudet %A Kenneth C. Smith %A Pedro Rosa-Neto %A François Bénard %A Sandra E. Black %A Katherine Zukotynski %T Machine Learning in Nuclear Medicine: Part 1—Introduction %D 2019 %R 10.2967/jnumed.118.223495 %J Journal of Nuclear Medicine %P 451-458 %V 60 %N 4 %X This article, the first in a 2-part series, provides an introduction to machine learning (ML) in a nuclear medicine context. This part addresses the history of ML and describes common algorithms, with illustrations of when they can be helpful in nuclear medicine. Part 2 focuses on current contributions of ML to our field, addresses future expectations and limitations, and provides a critical appraisal of what ML can and cannot do. %U https://jnm.snmjournals.org/content/jnumed/60/4/451.full.pdf