PT  - JOURNAL ARTICLE
AU  - Verena Pichler
AU  - Neydher Berroterán-Infante
AU  - Cecile Philippe
AU  - Chrysoula Vraka
AU  - Eva-Maria Klebermass
AU  - Theresa Balber
AU  - Sarah Pfaff
AU  - Lukas Nics
AU  - Markus Mitterhauser
AU  - Wolfgang Wadsak
TI  - An Overview of PET Radiochemistry, Part 1: The Covalent Labels <sup>18</sup>F, <sup>11</sup>C, and <sup>13</sup>N
AID  - 10.2967/jnumed.117.190793
DP  - 2018 Sep 01
TA  - Journal of Nuclear Medicine
PG  - 1350--1354
VI  - 59
IP  - 9
4099  - http://jnm.snmjournals.org/content/59/9/1350.short
4100  - http://jnm.snmjournals.org/content/59/9/1350.full
SO  - J Nucl Med2018 Sep 01; 59
AB  - This continuing educational article introduces the radiochemistry of PET tracers that exhibit a covalently bound radiolabel with the nuclides 11C, 13N, and 18F. The overall process of PET tracer production is explained, starting from the production of the radionuclide in a cyclotron; followed by the automatization process of the radiosynthesis, including the necessary steps for the respective synthesis; and finalized with the requirements for quality control.