PT  - JOURNAL ARTICLE
AU  - Jeffry A. Siegel
AU  - Bennett S. Greenspan
AU  - Alan H. Maurer
AU  - Andrew T. Taylor
AU  - William T. Phillips
AU  - Douglas Van Nostrand
AU  - Bill Sacks
AU  - Edward B. Silberstein
TI  - The BEIR VII Estimates of Low-Dose Radiation Health Risks Are Based on Faulty Assumptions and Data Analyses: A Call for Reassessment
AID  - 10.2967/jnumed.117.206219
DP  - 2018 Jul 01
TA  - Journal of Nuclear Medicine
PG  - 1017--1019
VI  - 59
IP  - 7
4099  - http://jnm.snmjournals.org/content/59/7/1017.short
4100  - http://jnm.snmjournals.org/content/59/7/1017.full
SO  - J Nucl Med2018 Jul 01; 59
AB  - The 2006 National Academy of Sciences Biologic Effects of Ionizing Radiation (BEIR) VII report is a well-recognized and frequently cited source on the legitimacy of the linear no-threshold (LNT) model—a model entailing a linear and causal relationship between ionizing radiation and human cancer risk. Linearity means that all radiation causes cancer and explicitly excludes a threshold below which radiogenic cancer risk disappears. However, the BEIR VII committee has erred in the interpretation of its selected literature; specifically, the in vitro data quoted fail to support LNT. Moreover, in vitro data cannot be considered as definitive proof of cancer development in intact organisms. This review is presented to stimulate a critical reevaluation by a BEIR VIII committee to reassess the validity, and use, of LNT and its derived policies.