PT  - JOURNAL ARTICLE
AU  - Emily B. Ehlerding
AU  - Lingyi Sun
AU  - Xiaoli Lan
AU  - Dexing Zeng
AU  - Weibo Cai
TI  - Dual-Targeted Molecular Imaging of Cancer
AID  - 10.2967/jnumed.117.199877
DP  - 2018 Mar 01
TA  - Journal of Nuclear Medicine
PG  - 390--395
VI  - 59
IP  - 3
4099  - http://jnm.snmjournals.org/content/59/3/390.short
4100  - http://jnm.snmjournals.org/content/59/3/390.full
SO  - J Nucl Med2018 Mar 01; 59
AB  - Molecular imaging is critical to personalized and precision medicine. Although singly targeted imaging probes are making an impact both clinically and preclinically, molecular imaging strategies using bispecific probes have enabled improved visualization of cancer in recent years through synergistic targeting of two ligands. In this Focus on Molecular Imaging review, we outline how peptide-, antibody-, and nanoparticle-based platforms have affected this emerging strategy, providing examples and pointing out areas in which the greatest clinical impact may be realized.