RT Journal Article
SR Electronic
T1 Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β−-Particle, and Auger Electron Emitters
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 91S
OP 96S
DO 10.2967/jnumed.116.186825
VO 58
IS Supplement 2
A1 Cristina Müller
A1 Nicholas P. van der Meulen
A1 Martina Benešová
A1 Roger Schibli
YR 2017
UL http://jnm.snmjournals.org/content/58/Supplement_2/91S.abstract
AB In recent years, new α-particle–, β−-particle–, and Auger electron–emitting radiometals—such as 67Cu, 47Sc, 166Ho, 161Tb, 149Tb, 212Pb/212Bi, 225Ac, and 213Bi—have been produced and evaluated (pre)clinically for therapeutic purposes. In this short review article, the most important routes of production of these radiometals are critically discussed, as are examples of their application in preclinical and clinical studies.