RT Journal Article
SR Electronic
T1 Comparison of Intraoperative γ-Probe Imaging and Postoperative SPECT/CT in Detection of Sentinel Nodes Related to the Ovary
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 243
OP 245
DO 10.2967/jnumed.116.183426
VO 58
IS 2
A1 Stéphanie C.J.M. Speth
A1 Roy F.P.M. Kruitwagen
A1 Marjolein Kleppe
A1 Ivo N.A. Pooters
A1 Toon Van Gorp
A1 Brigitte F.M. Slangen
A1 Boudewijn Brans
YR 2017
UL http://jnm.snmjournals.org/content/58/2/243.abstract
AB Tracer injection into ovarian ligaments has been shown to detect sentinel nodes (SNs) in patients with ovarian cancer. To determine the possibility that SNs are missed, this feasibility study compared their detection during surgery with their detection on postoperative SPECT/CT. Methods: In 8 patients (with either ovarian or endometrial cancer), after a staging lymphadenectomy including resection of SNs related to the ovary, SPECT/CT was performed within 24 h. Results: SPECT/CT identified hotspots in 4 patients at sites where SNs were resected. In 6 patients, additional sites were found, mainly in the pelvic region. Conclusion: Discrepancies between the γ-probe and SPECT/CT may be due to missed SNs during surgery, but with respect to pelvic hotspots, in most cases they are more probably related to remnants of tracer at injection sites. With respect to sites where SNs were resected, remaining hotspots may have been caused by residual lymphatic flow after resection.