RT Journal Article
SR Electronic
T1 Metabolic Imaging in Parkinson Disease
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 23
OP 28
DO 10.2967/jnumed.116.183152
VO 58
IS 1
A1 Sanne K. Meles
A1 Laura K. Teune
A1 Bauke M. de Jong
A1 Rudi A. Dierckx
A1 Klaus L. Leenders
YR 2017
UL http://jnm.snmjournals.org/content/58/1/23.abstract
AB This review focuses on recent human 18F-FDG PET studies in Parkinson disease. First, an overview is given of the current analytic approaches to metabolic brain imaging data. Next, we discuss how 18F-FDG PET studies have advanced understanding of the relation between distinct brain regions and associated symptoms in Parkinson disease, including cognitive decline. In addition, the value of 18F-FDG PET studies in differential diagnosis, identifying prodromal patients, and the evaluation of treatment effects are reviewed. Finally, anticipated developments in the field are addressed.