PT  - JOURNAL ARTICLE
AU  - Meles, Sanne K.
AU  - Teune, Laura K.
AU  - de Jong, Bauke M.
AU  - Dierckx, Rudi A.
AU  - Leenders, Klaus L.
TI  - Metabolic Imaging in Parkinson Disease
AID  - 10.2967/jnumed.116.183152
DP  - 2017 Jan 01
TA  - Journal of Nuclear Medicine
PG  - 23--28
VI  - 58
IP  - 1
4099  - http://jnm.snmjournals.org/content/58/1/23.short
4100  - http://jnm.snmjournals.org/content/58/1/23.full
SO  - J Nucl Med2017 Jan 01; 58
AB  - This review focuses on recent human 18F-FDG PET studies in Parkinson disease. First, an overview is given of the current analytic approaches to metabolic brain imaging data. Next, we discuss how 18F-FDG PET studies have advanced understanding of the relation between distinct brain regions and associated symptoms in Parkinson disease, including cognitive decline. In addition, the value of 18F-FDG PET studies in differential diagnosis, identifying prodromal patients, and the evaluation of treatment effects are reviewed. Finally, anticipated developments in the field are addressed.