RT Journal Article SR Electronic T1 Clinically Approved Nanoparticle Imaging Agents JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1833 OP 1837 DO 10.2967/jnumed.116.181362 VO 57 IS 12 A1 Thakor, Avnesh S. A1 Jokerst, Jesse V. A1 Ghanouni, Pejman A1 Campbell, Jos L. A1 Mittra, Erik A1 Gambhir, Sanjiv S. YR 2016 UL http://jnm.snmjournals.org/content/57/12/1833.abstract AB Nanoparticles are a new class of imaging agent used for both anatomic and molecular imaging. Nanoparticle-based imaging exploits the signal intensity, stability, and biodistribution behavior of submicron-diameter molecular imaging agents. This review focuses on nanoparticles used in human medical imaging, with an emphasis on radionuclide imaging and MRI. Newer nanoparticle platforms are also discussed in relation to theranostic and multimodal uses.